- Is there still a shortage of BCG vaccine?
- Why does BCG cause bladder cancer?
- Does bladder cancer spread fast?
- Why does bladder cancer keep coming back?
- What are the odds of bladder cancer returning?
- Is there a shortage of BCG for bladder cancer?
- How effective is BCG for bladder cancer?
- Can bladder cancer go into remission?
- What is the success rate of BCG treatment?
Is there still a shortage of BCG vaccine?
BCG production has slowed down Now the only source for several Western countries, Merck, has increased BCG production by more than 100 percent.
Despite this increase, Merck is still experiencing supply constraints.
And, as other global suppliers of BCG have depleted their stocks, worldwide shortages have become common..
Why does BCG cause bladder cancer?
Bacillus Calmette-Guerin or BCG is the most common intravesical immunotherapy for treating early-stage bladder cancer. It’s used to help keep the cancer from growing and to help keep it from coming back. BCG is a germ that’s related to the one that causes tuberculosis (TB), but it doesn’t usually cause serious disease.
Does bladder cancer spread fast?
High grade bladder cancer is likely to grow and spread quickly and become life threatening. High-grade cancers often need to be treated with chemotherapy, radiation or surgery. Low-grade cancers appear non-aggressive and have a low chance of becoming high grade.
Why does bladder cancer keep coming back?
Bladder cancer is caused by cells that mutate (change) and begin to grow in an uncontrolled way. Bladder cancer can be treated in many different ways.
What are the odds of bladder cancer returning?
Nearly three-fourths of patients diagnosed with high-risk bladder cancer will recur, progress, or die within ten years of their diagnosis.
Is there a shortage of BCG for bladder cancer?
The ongoing shortage of bacillus Calmette-Guérin (BCG), used intravesically to treat early-stage bladder cancer, continues to motivate experts to identify alternatives for the treatment of nonmuscle invasive bladder cancer (NMIBC). There has been a worldwide intermittent shortage of BCG for some years.
How effective is BCG for bladder cancer?
Doctors typically use BCG immunotherapy to treat stage 0 and stage 1 bladder cancer. The 5-year relative survival rate for people with stage 0 bladder cancer is 95.4 percent. For people with stage 1 bladder cancer, this figure is 69.4 percent.
Can bladder cancer go into remission?
Approximately 70% of bladder cancer patients go into remission after BCG therapy. Standard treatment for patients with bladder cancer that has invaded muscle tissue includes cisplatin-based chemotherapy followed by surgical removal of the bladder or radiation therapy and concomitant chemotherapy.
What is the success rate of BCG treatment?
A recent study was published evaluating maintenance BCG therapy . The authors observed a three-year recurrence free survival of 75.3% and disease-free survival of 96.1%. However, they reported a high complication rate of 81.5%.