Is Tamoxifen A Chemo Drug?

What kind of drug is tamoxifen?

Tamoxifen is in a class of medications known as antiestrogens.

It blocks the activity of estrogen (a female hormone) in the breast.

This may stop the growth of some breast tumors that need estrogen to grow..

What are the worst side effects of tamoxifen?

Side effects in menBlood clots in the large veins (deep vein thrombosis)Blood clots in the lungs (pulmonary emboli)Cataracts.Headache.Hot flashes.Impotence.Loss of sex drive.Nausea and vomiting.More items…

Why you should not take tamoxifen?

Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke. Aromatase inhibitors may cause muscle and joint aches and pains. Less common but more severe side effects of aromatase inhibitors are heart problems, osteoporosis, and broken bones.

What not eat or drink when taking tamoxifen?

The following foods (or major components) have been found to reduce the effectiveness of tamoxifen: Alcohol. Clementine juice. Grapefruit & grapefruit juice.

What drugs should not be taken with tamoxifen?

Certain medications used to treat depression should be avoided by women taking tamoxifen. The antidepressants paroxetine (Paxil) and fluoxetine (Prozac) have been found to increase women’s risk of dying of cancer if they are taking tamoxifen.

Is tamoxifen an immunosuppressant?

Taken together, the evidence from human, in vivo and in vitro studies presented here suggests that tamoxifen modulates immune function with differential effects on Th1 and Th2 immunity, which may be mediated through an estrogen-independent mechanism.

What are the long term effects of tamoxifen?

While long-term tamoxifen use among breast cancer survivors decreases their risk of developing the most common, less aggressive type of second breast cancer, such use is associated with a more than four-fold increased risk of a more aggressive, difficult-to-treat type of cancer in the breast opposite, or contralateral, …

Can tamoxifen be stopped suddenly?

Although tamoxifen is effective, many women stop taking it before they finish the full treatment course. Some may stop because of common side effects, such as hot flashes, vaginal dryness and mood swings. Others may worry about tamoxifen’s rare side effects, including blood clots and increased risk of uterine cancer.

Can breast cancer come back while on tamoxifen?

Cancers linked to treatment with tamoxifen Taking tamoxifen lowers the chance of hormone receptor-positive breast cancer coming back. It also lowers the risk of a second breast cancer. Tamoxifen does, however, increase the risk for uterine cancer (endometrial cancer and uterine sarcoma).

Can you take vitamin D with tamoxifen?

No interactions were found between tamoxifen and Vitamin D3.

Can you lose weight on tamoxifen?

Studies have shown that weight gain is not increased in women taking tamoxifen or anastrozole, but it is harder to study the effects of these drugs on a woman’s ability to lose weight. Regardless of the reasons for weight gain, weight loss requires calorie reduction.

Is Tamoxifen classified as chemotherapy?

Drug type: Tamoxifen is a hormone therapy. This medication is classified as an “anti-estrogen” (for more detail, see “How this drug works” section below).

Is tamoxifen a dangerous drug?

Tamoxifen can increase the risk of serious and life-threatening events, including uterine cancer, blood clots, and stroke. These events can be fatal. You should discuss the potential benefits and risks of this drug with your doctor.

How does tamoxifen make you feel?

Some people go through mood swings or feel low or depressed while they are taking tamoxifen. Or it may be harder to think clearly or concentrate. Tell your doctor or nurse if this is a problem, especially if you are feeling depressed. Tamoxifen may slightly increase your chances of having a blood clot.

What type of breast cancer is treated with tamoxifen?

In women at high risk of breast cancer, tamoxifen can be used to help lower the risk of developing breast cancer. For women who have been treated with breast-conserving surgery for ductal carcinoma in situ (DCIS) that is hormone receptor-positive, taking tamoxifen for 5 years lowers the chance of the DCIS coming back.

How do you prevent blood clots when taking tamoxifen?

Being immobile increased the risk of a blood clot. You should stop taking this medication 3 days prior to and during any prolonged immobilization (hospitalization or bed rest). When traveling, be sure to get up and move around frequently to reduce the risk of a clot.

Is tamoxifen an oral chemotherapy?

How should this medicine be used? Tamoxifen comes as a tablet to take by mouth. Tamoxifen is usually taken once or twice a day with or without food. Take tamoxifen at around the same time(s) every day.

Is Tamoxifen really necessary?

For breast cancer prevention, people are usually advised to take tamoxifen for five years. It’s also prescribed for five years for most patients with early stage, low-risk estrogen receptor-positive breast cancer. For those at higher risk, it can be taken as long as 10 years.

Can I drink green tea while taking tamoxifen?

You are taking tamoxifen: Green tea may increase risk of adverse effects of Tamoxifen. You are taking verapamil: Green tea may increase risk of adverse effects of Verapamil. You are taking irinotecan: By inhibiting elimination of irinotecan, EGCG may increase its toxicity.

Does tamoxifen age your skin?

One of the adverse effects of tamoxifen include hot flashes and vaginal dryness (reviewed in Neven and Vergotta 2001), but there have been no studies to determine effects on skin thickness, collagen content, elastic fibers or the formation of wrinkles.

Does tamoxifen make you gain weight?

Many people gain weight when they are treated with chemotherapy and steroids. Your extra weight may hang around and increase after chemotherapy if you also take hormonal therapy (tamoxifen or an aromatase inhibitor). If your body shifts into menopause because of chemotherapy, there’s a tendency to gain weight.